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PKC beta 抗体 (Internal Region)

The 兔 多克隆 anti-PKC beta antibody is suitable to detect PKC beta in samples from 人, 大鼠, 小鼠, 猴, 兔 和 Cow. It has been validated for WB 和 EIA.
产品编号 ABIN401431
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PKC beta 抗体 (Internal Region) (ABIN401431)

抗原

See all PKC beta (PRKCB) 抗体
PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

适用

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人, 大鼠, 小鼠, 猴, 兔, Cow

宿主

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克隆类型

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多克隆

标记

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This PKC beta antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Internal Region

    特异性

    This antibody is specific for PKC beta protein.

    交叉反应 (详细)

    Species reactivity (expected):Rabbit, Bovine, Rat, Mouse.
    Species reactivity (tested):Human, Monkey.

    纯化方法

    Affinity chromatography

    免疫原

    Synthetic peptide corresponding to an internal region of human Protein kinase C beta

    亚型

    IgG
  • 应用备注

    ELISA: 1/75,000 - 1/80,000. Western Blot: 1/1,000 - 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Az

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

    别名

    PRKCB

    背景

    Protein kinase C (PKC) beta is implicated as a potential important factor in cancer cell proliferation and angiogenesis. PKC is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Synonyms: PKC beta, PKC-B, PKC-beta, PKCB, PRKCB1, Protein kinase C beta type

    基因ID

    5579

    NCBI登录号

    NP_002729

    UniProt

    P05771

    途径

    WNT signaling, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling
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