FAP 抗体 (Internal Region)
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Quick Overview for FAP 抗体 (Internal Region) (ABIN401429)
抗原
See all FAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody is known to react with Mouse FAP protein.
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交叉反应 (详细)
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Species reactivity (expected):Rat, Human.
Species reactivity (tested):Mouse. -
纯化方法
- Immunoffinity Chromatography.
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免疫原
- Synthetic peptide corresponding to an internal region of mouse FAP protein
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亚型
- IgG
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应用备注
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ELISA: 1/100000. Western Blot: 1/500-1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.65 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- FAP (Fibroblast Activation Protein, alpha (FAP))
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别名
- Seprase / FAP
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背景
- Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.Synonyms: 170 kDa melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Integral membrane serine protease
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基因ID
- 14089
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NCBI登录号
- NP_032012
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UniProt
- P97321
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途径
- Tube Formation
抗原
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