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EIF3E 抗体 (C-Term)

EIF3E 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401422
发货至: 中国
  • 抗原 See all EIF3E 抗体
    EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 45
    • 22
    • 18
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 猴
    宿主
    • 43
    • 1
    • 1
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 28
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF3E antibody is un-conjugated
    应用范围
    • 36
    • 19
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific for Mouse eIF3S6/Int6 protein.
    交叉反应 (详细)
    Species reactivity (expected):Human, Rat, Canine, Bovine, Monkey.
    Species reactivity (tested):Mouse.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide corresponding to a region near the C-terminus of mouse EIF3S6/Int6 . Genename: EIF3E
    亚型
    IgG
    Top Product
    Discover our top product EIF3E Primary Antibody
  • 应用备注
    Suitable for use in ELISA (1/80,000) and Western Blot (1/1,000). Expect a band approx. 48 kDa in size corresponding to eIF3S6/Int6 by Western blotting in theappropriate cell lysate or extract. This antibody is capable of detecting bothover-expressed and endogenous eIF3S6/Int6.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.8 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
    别名
    EIF3E / EIF3S6 (EIF3E 产品)
    别名
    EIF3-P48 antibody, EIF3S6 antibody, INT6 antibody, eIF3-p46 antibody, 48kDa antibody, Eif3s6 antibody, Int6 antibody, eIF3-p48 antibody, eif3-p48 antibody, eif3s6 antibody, eif3s6-A antibody, eIF3e antibody, eIF3-S6 antibody, eif3s6-B antibody, EIF3SE antibody, eif3s6b antibody, im:7147439 antibody, QtsA-18056 antibody, eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit E antibody, eukaryotic translation initiation factor 3 subunit E L homeolog antibody, eukaryotic translation initiation factor 3 subunit 6 antibody, eukaryotic translation initiation factor 3 subunit E S homeolog antibody, eukaryotic translation initiation factor 3, subunit E, a antibody, Eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit E, b antibody, EIF3E antibody, Eif3e antibody, eif3e antibody, eif3e.L antibody, LOC692936 antibody, eif3e.S antibody, eif3ea antibody, eif-3.E antibody, eif3eb antibody, LOC108348260 antibody, int6 antibody
    背景
    Int6 is a candidate tumor suppressor in multiple neoplasms, and in particular, breast and lung cancers. The Int6 locus was initially identified as a common insertion site (CIS) in a genetic screen for transforming sequences in a breast cancer mouse model system. Insertion of mouse mammary tumor virus (MMTV) into this locus results in the production of an amino-terminal truncated gene product. Expression of the truncated Int6 product corresponds to cellular transformation in both in vivo and in vitro systems. This gene product plays a role in regulating translation initiation and is a component of the eIF3 translation initiation complex. There is evidence that suggests that Int6 may impart a negative role in the general translational machinery while promoting an increase in the expression of a subset of stress-responsive genes. Taken together, it is of great interest to further study the mechanism by which Int6 is involved in regulating cell growth.Synonyms: Eukaryotic translation initiation factor 3 subunit 6, Eukaryotic translation initiation factor 3 subunit E, INT6, Viral integration site protein INT-6 homolog, eIF-3 p48
    基因ID
    16341
    NCBI登录号
    NP_032414
    UniProt
    P60229
    途径
    Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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