EIF3E 抗体 (C-Term)
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Quick Overview for EIF3E 抗体 (C-Term) (ABIN401422)
抗原
See all EIF3E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is specific for Mouse eIF3S6/Int6 protein.
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交叉反应 （详细）
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Species reactivity (expected):Human, Rat, Canine, Bovine, Monkey.
Species reactivity (tested):Mouse. -
纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic peptide corresponding to a region near the C-terminus of mouse EIF3S6/Int6 . Genename: EIF3E
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (Middle Region) antibody
EIF3E 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 346-445) antibodyEIF3E 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 1-445) antibodyEIF3E 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) antibodyEIF3E 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 36-85) antibodyEIF3E 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) antibodyKD Validated EIF3E 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2455 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 248-276) antibodyEIF3E 适用: 人, 斑马鱼 WB 宿主: 兔 Polyclonal RB40515 unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (N-Term) antibodyEIF3E 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 1-445) antibodyEIF3E 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (C-Term) antibodyVerified EIF3E 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Suitable for use in ELISA (1/80,000) and Western Blot (1/1,000). Expect a band approx. 48 kDa in size corresponding to eIF3S6/Int6 by Western blotting in theappropriate cell lysate or extract. This antibody is capable of detecting bothover-expressed and endogenous eIF3S6/Int6.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.8 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
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别名
- EIF3E / EIF3S6
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背景
- Int6 is a candidate tumor suppressor in multiple neoplasms, and in particular, breast and lung cancers. The Int6 locus was initially identified as a common insertion site (CIS) in a genetic screen for transforming sequences in a breast cancer mouse model system. Insertion of mouse mammary tumor virus (MMTV) into this locus results in the production of an amino-terminal truncated gene product. Expression of the truncated Int6 product corresponds to cellular transformation in both in vivo and in vitro systems. This gene product plays a role in regulating translation initiation and is a component of the eIF3 translation initiation complex. There is evidence that suggests that Int6 may impart a negative role in the general translational machinery while promoting an increase in the expression of a subset of stress-responsive genes. Taken together, it is of great interest to further study the mechanism by which Int6 is involved in regulating cell growth.Synonyms: Eukaryotic translation initiation factor 3 subunit 6, Eukaryotic translation initiation factor 3 subunit E, INT6, Viral integration site protein INT-6 homolog, eIF-3 p48
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基因ID
- 16341
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NCBI登录号
- NP_032414
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UniProt
- P60229
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途径
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
抗原
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