IL7R 抗体 (pTyr449)
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北京 101111
Quick Overview for IL7R 抗体 (pTyr449) (ABIN401417)
抗原
See all IL7R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr449
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交叉反应 （详细）
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Species reactivity (expected):Human, Rat.
Species reactivity (tested):Mouse. -
纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide corresponding to residues near Y449 of mouse IL-7 protein
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亚型
- IgG
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anti-Interleukin 7 Receptor (IL7R) (AA 173-260) antibody
IL7R 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) (AA 21-239) antibodyIL7R 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 3F5D9 unconjugated
anti-Interleukin 7 Receptor (IL7R) (AA 21-239) antibodyIL7R 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) (N-Term) antibodyIL7R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) (AA 21-236) antibodyIL7R 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal IL7R-2751 unconjugated
anti-Interleukin 7 Receptor (IL7R) (pTyr449) antibodyIL7R 适用: 人 FACS, WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) antibodyIL7R 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) antibody (APC)IL7R 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal A7R34 APC
anti-Interleukin 7 Receptor (IL7R) (Ser552) antibodyIL7R 适用: 人, 小鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) (AA 1-459) antibodyIL7R 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA: 1/100,000. Western Blot: 1/1,000 - 1/10,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.1 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- IL7R (Interleukin 7 Receptor (IL7R))
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别名
- CD127 / IL7R
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背景
- Interleukin-7 is a glycoprotein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R), the active receptor is an alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. The human and mouse sequence is nearly identical. In humans, severe combined immunodeficiency is caused by genetic defects in IL-7 receptor. The tyrosine residue at the 449 position is a critical signaling site of the intracellular domain of IL-7 receptor. This site is rapidly phosphorylated by janus kinases after the IL-7 receptor is engaged.Synonyms: IL-7R-alpha, IL7 receptor alpha, Interleukin-7 receptor subunit alpha
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基因ID
- 10090
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UniProt
- P16872
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
抗原
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