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IL7R 抗体 (C-Term)

IL7R 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401416
发货至: 中国
  • 抗原 See all IL7R 抗体
    IL7R (Interleukin 7 Receptor (IL7R))
    抗原表位
    • 24
    • 16
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 109
    • 49
    • 26
    • 7
    • 4
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 81
    • 35
    • 27
    • 1
    • 1
    克隆类型
    • 81
    • 62
    • 2
    多克隆
    标记
    • 62
    • 11
    • 10
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL7R antibody is un-conjugated
    应用范围
    • 84
    • 77
    • 45
    • 26
    • 26
    • 13
    • 12
    • 9
    • 8
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (expected):Human, Rat.
    Species reactivity (tested):Mouse.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic peptide corresponding to a region near the carboxy terminus of mouse IL-7 protein
    亚型
    IgG
    Top Product
    Discover our top product IL7R Primary Antibody
  • 应用备注
    ELISA: 1/100,000. Western Blot: 1/1,000 - 1/10,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    IL7R (Interleukin 7 Receptor (IL7R))
    别名
    CD127 / IL7R (IL7R 产品)
    别名
    IL7R antibody, CD127 antibody, IL-7Ralpha antibody, CDW127 antibody, IL-7R-alpha antibody, IL7RA antibody, ILRA antibody, IL-7RA antibody, interleukin 7 receptor antibody, IL7R antibody, Il7r antibody
    背景
    Interleukin-7 is a glycoprotein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R), the active receptor is an alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. The human and mouse sequence is nearly identical. In humans, severe combined immunodeficiency is caused by genetic defects in IL-7 receptor. The tyrosine residue at the 449 position is a critical signaling site of the intracellular domain of IL-7 receptor. This site is rapidly phosphorylated by janus kinases after the IL-7 receptor is engaged.Synonyms: IL-7R-alpha, IL7 receptor alpha, Interleukin-7 receptor subunit alpha
    基因ID
    10090
    UniProt
    P16872
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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