DAXX 抗体 (AA 261-274)
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Quick Overview for DAXX 抗体 (AA 261-274) (ABIN401370)
抗原
See all DAXX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-274
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特异性
- This antibody is directed against DAXX protein.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide corresponding to amino acids 261-274 of human DAXX protein
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亚型
- IgG
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应用备注
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ELISA: 1/7,000 - 1/45,000. Western Blot: 1/200 - 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.06 mg/mL (by UV absorbance at 280)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- DAXX (Death-Domain Associated Protein (DAXX))
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别名
- DAXX
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背景
- DAXX, the Death domain-associated protein 6 (also named Fas death domain-associated protein, ETS1-associated protein 1 or EAP1), functions in part as a transcriptional co-repressor through its interaction with a number of nuclear, DNA-associated proteins, such as histone deacetylase II, core histones H2A, H2B, H3 and H4, and Dek, a chromatinassociated protein reported to change the topology of DNA in chromatin in vitro (1). DAXX also interacts with p73, and is involved in the regulation of the cell cycle and apoptosis through transcriptional regulation of p53 and possibly its family members (2).Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein
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基因ID
- 1616
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NCBI登录号
- NP_001135441
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UniProt
- Q9UER7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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