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DAXX 抗体 (AA 261-274)

The 兔 多克隆 anti-DAXX antibody (ABIN401370) specifically detects DAXX in WB 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN401370
发货至: 中国
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Quick Overview for DAXX 抗体 (AA 261-274) (ABIN401370)

抗原

See all DAXX 抗体
DAXX (Death-Domain Associated Protein (DAXX))

适用

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人, 小鼠, 大鼠

宿主

  • 154
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克隆类型

  • 132
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多克隆

标记

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This DAXX antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 24
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    AA 261-274

    特异性

    This antibody is directed against DAXX protein.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Purified

    免疫原

    Synthetic peptide corresponding to amino acids 261-274 of human DAXX protein

    亚型

    IgG
  • 应用备注

    ELISA: 1/7,000 - 1/45,000. Western Blot: 1/200 - 1/2000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.06 mg/mL (by UV absorbance at 280)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    DAXX

    背景

    DAXX, the Death domain-associated protein 6 (also named Fas death domain-associated protein, ETS1-associated protein 1 or EAP1), functions in part as a transcriptional co-repressor through its interaction with a number of nuclear, DNA-associated proteins, such as histone deacetylase II, core histones H2A, H2B, H3 and H4, and Dek, a chromatinassociated protein reported to change the topology of DNA in chromatin in vitro (1). DAXX also interacts with p73, and is involved in the regulation of the cell cycle and apoptosis through transcriptional regulation of p53 and possibly its family members (2).Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein

    基因ID

    1616

    NCBI登录号

    NP_001135441

    UniProt

    Q9UER7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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