CTCFL 抗体 (AA 9-26)
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Quick Overview for CTCFL 抗体 (AA 9-26) (ABIN401325)
抗原
See all CTCFL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-26
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特异性
- This antibody is directed against the BORIS protein.
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交叉反应 (详细)
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Species reactivity (expected):Chimpanzee.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide corresponding aa 9-26 of human BORIS protein
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亚型
- IgG
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应用备注
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ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.28 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
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别名
- CTCFL / BORIS
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背景
- BORIS (Brother of the Regulator of Imprinted Sites) also known as CCCTC-binding factor-like protein, is normally only expressed in the testis and expressed in a mutually exclusive manner with CTCF during male germ cell development. However, previous studies have shown that BORIS is abnormally activated in a wide range of human cancers. Expression of BORIS in normally BORIS-negative cells promotes cell growth that may lead to transformation. BORIS maps to the cancer-associated amplification region thought to contain an oncogene or dominant-immortalizing gene. BORIS is a candidate protein for the epigenetic reprogramming factor acting in the male germ line. BORIS is found in both the nucleus and cytoplasm.Synonyms: Brother of the regulator of imprinted sites, CCCTC-binding factor, CT27, CTCF paralog, CTCF-T, CTCF-like protein, Cancer/testis antigen 27, Transcriptional repressor CTCFL, Zinc finger protein CTCF-T
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基因ID
- 140690
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NCBI登录号
- NP_542185
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UniProt
- Q8NI51
抗原
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