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HDAC1 抗体 (AA 466-482)

The 兔 多克隆 anti-HDAC1 antibody is suitable to detect HDAC1 in samples from 人, 小鼠, 大鼠, Cow, 小鸡 和 Chimpanzee. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN401309
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HDAC1 抗体 (AA 466-482) (ABIN401309)

抗原

See all HDAC1 抗体
HDAC1 (Histone Deacetylase 1 (HDAC1))

适用

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人, 小鼠, 大鼠, Cow, 小鸡, Chimpanzee

宿主

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克隆类型

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多克隆

标记

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This HDAC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    AA 466-482

    特异性

    This antibody is directed against HDAC-1 protein.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Chimpanzee, Bovine, Chicken.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Synthetic peptide corresponding to amino acids 466-482 of Human HDAC-1

    亚型

    IgG
  • 应用备注

    Western Blot: 1/1,000 - 1/5,000. ELISA: 1/10,000 - 1/50,000. Immunohistochemistry: 1/200 - 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.33 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    HDAC1 (Histone Deacetylase 1 (HDAC1))

    别名

    HDAC1

    背景

    HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.Synonyms: HD1, Histone deacetylase 1, RPD3L1

    基因ID

    3065

    NCBI登录号

    NP_004955

    UniProt

    Q13547

    途径

    Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
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