UBASH3B 抗体 (C-Term)
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- 抗原 See all UBASH3B (STS1) 抗体
- UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBASH3B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is directed against Sts-1 protein.
- 交叉反应 （详细）
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Species reactivity (expected):Rat, Human.
Species reactivity (tested):Mouse. - 纯化方法
- Affinity chromatography
- 免疫原
- Synthetic peptide corresponding to the C-terminus of mouse Sts-1
- 亚型
- IgG
- Top Product
- Discover our top product STS1 Primary Antibody
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anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 1-300) antibody
STS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 344-441) antibodySTS1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (C-Term) antibodySTS1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 1-300) antibodySTS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) antibodySTS1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) antibodySTS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 564-613) antibodySTS1 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 344-442) antibodySTS1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
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- 应用备注
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ELISA: 1/2,000 - 1/10,000. Western Blot: 1/500 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.63 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
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- 抗原
- UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))
- 别名
- UBASH3B / STS1 (STS1 产品)
- 别名
- STS-1 antibody, STS1 antibody, TULA-2 antibody, p70 antibody, 2810457I06Rik antibody, BB125008 antibody, RGD1310357 antibody, Sts-1 antibody, ubiquitin associated and SH3 domain containing B antibody, ubiquitin associated and SH3 domain containing, B antibody, UBASH3B antibody, Ubash3b antibody
- 背景
- Sts-1 is a protein that inhibits endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. Sts-1 and Sts-2 (formerly p70 and Clip4, respectively) have been found to interact with Cbl, an ubiquitin ligase that plays a critical role in attenuation of receptor tyrosine kinase signaling by inducing ubiquitination and promoting their sorting for endosomal degradation. Sts-1 and Sts-2 contain SH3 domains that interact with Cbl, Ub-associated domains, which bind directly to mono-Ub or to the EGFR/Ub chimera, as well as phosphoglycerate mutase domains that mediate oligomerization of Sts-1/2. Sts-1 and Sts-2 also have been found to negatively regulate signaling pathways that control T cell receptors, which in turn affect the extent and duration of the T cell response to foreign pathogens.Synonyms: Cbl-interacting protein p70, KIAA1959, STS-1, Suppressor of T-cell receptor signaling 1, Ubiquitin-associated and SH3 domain-containing protein B
- 基因ID
- 84959
- NCBI登录号
- NP_116262
- UniProt
- Q8TF42
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