UBASH3B 抗体 (C-Term)
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Quick Overview for UBASH3B 抗体 (C-Term) (ABIN401302)
抗原
See all UBASH3B (STS1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is directed against Sts-1 protein.
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交叉反应 （详细）
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Species reactivity (expected):Rat, Human.
Species reactivity (tested):Mouse. -
纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide corresponding to the C-terminus of mouse Sts-1
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亚型
- IgG
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anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 1-300) antibody
STS1 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 344-441) antibodySTS1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) antibodySTS1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 1-300) antibodySTS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (C-Term) antibodySTS1 适用: 人, 小鼠 IHC, WB, ELISA, FM 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) antibodySTS1 适用: 人, 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 344-442) antibodySTS1 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 564-613) antibodySTS1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/2,000 - 1/10,000. Western Blot: 1/500 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.63 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))
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别名
- UBASH3B / STS1
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背景
- Sts-1 is a protein that inhibits endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. Sts-1 and Sts-2 (formerly p70 and Clip4, respectively) have been found to interact with Cbl, an ubiquitin ligase that plays a critical role in attenuation of receptor tyrosine kinase signaling by inducing ubiquitination and promoting their sorting for endosomal degradation. Sts-1 and Sts-2 contain SH3 domains that interact with Cbl, Ub-associated domains, which bind directly to mono-Ub or to the EGFR/Ub chimera, as well as phosphoglycerate mutase domains that mediate oligomerization of Sts-1/2. Sts-1 and Sts-2 also have been found to negatively regulate signaling pathways that control T cell receptors, which in turn affect the extent and duration of the T cell response to foreign pathogens.Synonyms: Cbl-interacting protein p70, KIAA1959, STS-1, Suppressor of T-cell receptor signaling 1, Ubiquitin-associated and SH3 domain-containing protein B
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基因ID
- 84959
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NCBI登录号
- NP_116262
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UniProt
- Q8TF42
抗原
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