FANCF 抗体 (Internal Region)
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Quick Overview for FANCF 抗体 (Internal Region) (ABIN401270)
抗原
See all FANCF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This affinity purified antibody is directed against FANCF protein.
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交叉反应 （详细）
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Species reactivity (expected):Chimpanzee (100 %).
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity chromatography
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免疫原
- Synthetic peptide corresponding to an internal amino acid sequence of human FANCF
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亚型
- IgG
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anti-Fanconi Anemia, Complementation Group F (FANCF) (AA 1-374) antibody
FANCF 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group F (FANCF) antibodyFANCF 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group F (FANCF) (AA 1-91) antibodyFANCF 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Fanconi Anemia, Complementation Group F (FANCF) (AA 217-228) antibodyVerified FANCF 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group F (FANCF) (C-Term) antibodyVerified FANCF 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group F (FANCF) (AA 295-341) antibodyFANCF 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 15,000 - 1: 60,000. Western blot: 1: 1,000 - 1: 5,000 (Expect a band approximately 42 kDa in size correspondingto FANCF in the appropriate human tissue).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.19 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- FANCF (Fanconi Anemia, Complementation Group F (FANCF))
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别名
- FANCF
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背景
- FANCF (also called Protein FACF or Fanconi Anemia Group F protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCF has also been implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCF belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. FANCF is found within the nucleus. Defects in FANCF are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level, it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.Synonyms: FACF, Fanconi anemia group F protein
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基因ID
- 2188
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NCBI登录号
- NP_073562
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UniProt
- Q9NPI8
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途径
- DNA Damage Repair
抗原
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