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FANCF 抗体 (Internal Region)

FANCF 适用: 人, Chimpanzee WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401270
发货至: 中国
  • 抗原 See all FANCF 抗体
    FANCF (Fanconi Anemia, Complementation Group F (FANCF))
    抗原表位
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 18
    • 2
    • 1
    人, Chimpanzee
    宿主
    • 15
    • 2
    • 2
    克隆类型
    • 18
    • 1
    多克隆
    标记
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FANCF antibody is un-conjugated
    应用范围
    • 11
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This affinity purified antibody is directed against FANCF protein.
    交叉反应 (详细)
    Species reactivity (expected):Chimpanzee (100 %).
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity chromatography
    免疫原
    Synthetic peptide corresponding to an internal amino acid sequence of human FANCF
    亚型
    IgG
    Top Product
    Discover our top product FANCF Primary Antibody
  • 应用备注
    ELISA: 1: 15,000 - 1: 60,000. Western blot: 1: 1,000 - 1: 5,000 (Expect a band approximately 42 kDa in size correspondingto FANCF in the appropriate human tissue).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.19 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FANCF (Fanconi Anemia, Complementation Group F (FANCF))
    别名
    FANCF (FANCF 产品)
    别名
    FAF antibody, A730016A17 antibody, RGD1561456 antibody, Fanconi anemia complementation group F L homeolog antibody, Fanconi anemia, complementation group F antibody, Fanconi anemia complementation group F antibody, fancf.L antibody, fancf antibody, FANCF antibody, Fancf antibody
    背景
    FANCF (also called Protein FACF or Fanconi Anemia Group F protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCF has also been implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCF belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. FANCF is found within the nucleus. Defects in FANCF are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level, it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.Synonyms: FACF, Fanconi anemia group F protein
    基因ID
    2188
    NCBI登录号
    NP_073562
    UniProt
    Q9NPI8
    途径
    DNA Damage Repair
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