FANCC 抗体 (AA 96-112)
Our Local Distributor
北京 101111
Quick Overview for FANCC 抗体 (AA 96-112) (ABIN401268)
抗原
See all FANCC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 96-112
-
特异性
- This antibody is directed against human FANCC protein.
-
交叉反应 （详细）
-
Species reactivity (expected):Chimpanzee (100 %).
Species reactivity (tested):Human. -
纯化方法
- Affinity Purified
-
免疫原
- Synthetic peptide corresponding to amino acids 96-112 of Human FANCC
-
亚型
- IgG
-
-
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 319-558) antibody
FANCC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-558) antibodyFANCC 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (Center) antibodyFANCC 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 527-555), (C-Term) antibodyFANCC 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB24076 unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (C-Term) antibodyFANCC 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-100) antibodyFANCC 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6E7 unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-210) antibodyFANCC 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) antibodyKD Validated FANCC 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB8340 unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 529-558), (C-Term) antibodyFANCC 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (N-Term) antibodyFANCC 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- ELISA: 1: 20,000 - 1: 80,000. Western blot: 1: 1,000 - 1: 3,000 (Expect a band approximately 63 kDa in size correspondingto FANCC in the appropriate human tissue).
-
限制
- 仅限研究用
-
-
-
浓度
- 1.45 mg/mL (by UV absorbance at 280 nm)
-
缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
-
-
- FANCC (Fanconi Anemia, Complementation Group C (FANCC))
-
别名
- FANCC
-
背景
- FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is ubiquitously expressed. Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNAdamaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.Synonyms: FAC, FACC, Fanconi anemia group C protein
-
基因ID
- 2176
-
NCBI登录号
- NP_000127
-
UniProt
- Q00597
-
途径
- DNA Damage Repair
抗原
-
