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SFRP1 抗体

SFRP1 适用: 人, 小鼠, 大鼠, Cow WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401251
发货至: 中国
  • 抗原 See all SFRP1 抗体
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    适用
    • 54
    • 41
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    • 1
    • 1
    人, 小鼠, 大鼠, Cow
    宿主
    • 69
    • 9
    • 2
    • 2
    克隆类型
    • 71
    • 11
    多克隆
    标记
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    This SFRP1 antibody is un-conjugated
    应用范围
    • 60
    • 31
    • 25
    • 13
    • 13
    • 6
    • 6
    • 4
    • 4
    • 4
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This affinity purified antibody is directed against Human SFRP protein. A BLAST analysis was used to suggest reactivity with this protein from Human based on 100 % homology for the immunogen sequence. Expect cross reactivity with SFRP1 from Mouse, Rat and Bovine sources as only a single amino acid residue change is found within the immunogen sequence (91 % positive by BLAST). Cross reactivity with SFRP1 homologues from other sources has not been determined.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat and Bovine.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide corresponding to a 12 amino acid region of Human Sfrp1 protein
    亚型
    IgG
    Top Product
    Discover our top product SFRP1 Primary Antibody
  • 应用备注
    ELISA: 1: 5,000 - 1: 25,000. Immunohistochemistry on paraffin sections: 1: 800. Western blot: 1: 200 - 1: 2,000 (Expect a band approximately 37 kDa in size corresponding toSfrp1 in the appropriate cell lysate or extract).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.56 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide, None
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    别名
    SFRP1 (SFRP1 产品)
    别名
    FRP antibody, FRP-1 antibody, FRP1 antibody, FrzA antibody, SARP2 antibody, 2210415K03Rik antibody, AW011917 antibody, AW107218 antibody, AW742929 antibody, sFRP-1 antibody, CSFRP1 antibody, SFRP1 antibody, XfrzA antibody, frp antibody, frp-1 antibody, frp1 antibody, frzA antibody, sarp2 antibody, sfrp1 antibody, LOC100231868 antibody, Srfp1a antibody, wu:fd19b09 antibody, secreted frizzled related protein 1 antibody, secreted frizzled-related protein 1 antibody, Secreted frizzled-related protein 1 antibody, secreted frizzled-related protein 1a antibody, secreted frizzled-related protein 1b antibody, SFRP1 antibody, Sfrp1 antibody, sfrp1 antibody, sfrp1a antibody, sfrp1b antibody
    背景
    SFRP1 (also known as FRP, FRP1, SARP2, Secreted Apoptosis-related Protein 2, Secreted Frizzledrelated Protein and Secreted frizzled-related protein 1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.Synonyms: FRP, FRP-1, FRP1, SARP-2, SARP2, SFRP-1, Secreted apoptosis-related protein 2, Secreted frizzled-related protein 1
    分子量
    35.4 kDa (Predicted)
    基因ID
    6422
    NCBI登录号
    NP_003003
    UniProt
    Q8N474
    途径
    WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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