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UBE2N 抗体 (AA 40-51)

UBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 小鸡, 非洲爪蟾, Chimpanzee, Macaque WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN401175
发货至: 中国
  • 抗原 See all UBE2N 抗体
    UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
    抗原表位
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 40-51
    适用
    • 38
    • 34
    • 32
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 小鸡, 非洲爪蟾, Chimpanzee, Macaque
    宿主
    • 48
    • 4
    • 1
    山羊
    克隆类型
    • 40
    • 13
    多克隆
    标记
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2N antibody is un-conjugated
    应用范围
    • 20
    • 16
    • 13
    • 13
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is directed against UBC13 protein.
    交叉反应 (详细)
    Species reactivity (expected):Canine, Bovine, Xenopus laevis, Xenopus tropicalis, Zebrafish, Rat, Mouse, Chimpanzee, Macaque, Chicken.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic peptide corresponding to amino acids 40-51 of human UBC13 protein
    亚型
    IgG
    Top Product
    Discover our top product UBE2N Primary Antibody
  • 应用备注
    ELISA: 1/5,000 - 1/25,000. Western Blot: 1/500 - 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.25 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
    Abstract
    UBE2N 产品
    别名
    UBC13 antibody, UbcH-ben antibody, UbcH13 antibody, 1500026J17Rik antibody, AL022654 antibody, BB101821 antibody, ube2n antibody, wu:fb11b03 antibody, wu:fc08b06 antibody, zgc:55726 antibody, ubc13 antibody, ubch-ben antibody, UBE2N antibody, ube2nl antibody, zgc:63901 antibody, ubiquitin conjugating enzyme E2 N antibody, ubiquitin-conjugating enzyme E2N antibody, ubiquitin conjugating enzyme E2 N S homeolog antibody, ubiquitin-conjugating enzyme E2Na antibody, ubiquitin-conjugating enzyme E2Nb antibody, UBE2N antibody, Ube2n antibody, ube2n.S antibody, ube2na antibody, LOC100533434 antibody, ube2n antibody, ube2nb antibody
    背景
    UBC13 is a member of the E2 ubiquitin-conjugating enzyme family also known as Ubiquitin-conjugating enzyme E2 N, Ubiquitin-protein ligase N, Ubiquitin carrier protein N and Bendless-like ubiquitin-conjugating enzyme. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBC13 forms a heterodimer with UBE2V2 which then catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of polyubiquitination does not lead to protein degradation by the proteasome. UBC13 also mediates transcriptional activation of target genes and plays a role in the control of progress through the cell cycle and differentiation, as well as error-free DNA repair. UBC13 also contributes to the survival of cells after DNA damage.Synonyms: Bendless-like ubiquitin-conjugating enzyme, UBC13, Ubiquitin carrier protein N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-protein ligase N
    基因ID
    7334
    NCBI登录号
    NP_003339
    UniProt
    P61088
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
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