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Interleukin 17a 抗体

The 兔 多克隆 anti-Interleukin 17a antibody (ABIN401100) specifically detects Interleukin 17a in WB, Neut 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN401100
发货至: 中国
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Quick Overview for Interleukin 17a 抗体 (ABIN401100)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

适用

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宿主

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克隆类型

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多克隆

标记

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This Interleukin 17a antibody is un-conjugated

应用范围

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Western Blotting (WB), Neutralization (Neut), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody will recognize both native and recombinant human IL17-A in cell supernatants and certain body fluids.

    纯化方法

    Purified

    免疫原

    Recombinant human IL17-A protein

    亚型

    IgG
  • 应用备注

    ELISA: 1/20000 - 1/100000. Western Blot: 1/500 - 1/2000. Neutralization: 1/400.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 0.1 mL of deionized water (or equivalent).

    浓度

    1.0 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    Interleukin-17A (IL17A)

    背景

    IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8 in rodents) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NFkappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL-17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17

    基因ID

    3605

    NCBI登录号

    NP_002181

    UniProt

    Q16552
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