FKBP8 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for FKBP8 抗体 (Internal Region) (ABIN401051)
抗原
See all FKBP8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- This antibody is specific for FKBP8 protein.
-
交叉反应 （详细）
-
Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography on Protein A
-
免疫原
- Synthetic peptide corresponding to an internal region of human FKBP8 protein
-
亚型
- IgG
-
-
anti-FK506 Binding Protein 8, 38kDa (FKBP8) antibody
FKBP8 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 58-190) antibodyFKBP8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 60-270) antibodyFKBP8 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) antibodyKD Validated FKBP8 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2450 unconjugated Recombinant Antibody
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 199-226) antibodyFKBP8 适用: 人 WB 宿主: 兔 Polyclonal RB27518 unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-329) antibodyFKBP8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 93-339) antibodyFKBP8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 7-2# unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 1-413) antibodyFKBP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (N-Term) antibodyFKBP8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (C-Term) antibodyFKBP8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/25000. Western Blot: 1/500 - 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 2.3 mg/mL (by UV absorbance at 280 nm)
-
缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
-
- FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
-
别名
- FKBP8 / FKBP38
-
背景
- FKBP8 (also known as FK506-binding protein 38) is a member of the immunophilin family that has been implicated to play an important role in apoptosis through its involvement in the mechanism that targets Bcl-2 and Bcl-xL to the outer mitochondrial membrane (OMM). Suppression of endogenous FKBP8 by RNAi or transfection of a mutant FKBP8 missing the transmembrane domain necessary for mitochondrial insertion, resulted in the translocation of Bcl-2 and Bcl-xL from the OMM to the cytosol. It has also been suggested that FKBP8 may play a role in the cross-talk between the Bcl-2 and the Calcineurin/NF-AT apoptosis signaling pathways and in cell size regulation through interactions with tuberous sclerosis genes.Synonyms: 38 kDa FK506-binding protein, FK506-binding protein 8, Peptidyl-prolyl cis-trans isomerase FKBP8, Rotamase
-
基因ID
- 23770
-
NCBI登录号
- NP_036313
-
UniProt
- Q14318
-
途径
- Autophagy
抗原
-
