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CD28 抗体

This anti-CD28 antibody is a 小鼠 单克隆 antibody detecting CD28 in FACS, WB, IF, IP, Func 和 IHC (fro). Suitable for 人 和 灵长类.
产品编号 ABIN400890
发货至: 中国

Quick Overview for CD28 抗体 (ABIN400890)

抗原

See all CD28 抗体
CD28

适用

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人, 灵长类

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD28 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

CD28-2
  • 特异性

    The antibody reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.

    产品特性

    Synonyms: TP44, T-cell-specific surface glycoprotein CD28

    纯化方法

    Affinity Chromatography on Protein A

    过滤

    0.2 μm filtered

    免疫原

    DC28. 1. 3. 3 hybridoma cells

    亚型

    IgG1
  • 应用备注

    Flow Cytometry. Immunoprecipitation. Western blot. Immunohistochemistry on frozen sections. Immunoflourescence. Functional Application. T cell costimulation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Azide free Phosphate Buffered Saline (PBS), pH ~7.4, 0.2 μm filter sterilization. Endotoxin level is less than 10 EU/mg of the protein, as determined by the LAL test.

    储存液

    Azide free

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD28

    别名

    CD28

    背景

    CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Synonyms: T-cell-specific surface glycoprotein CD28, TP44

    基因ID

    940

    UniProt

    P10747

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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