TDP1 抗体 (N-Term)
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北京 101111
Quick Overview for TDP1 抗体 (N-Term) (ABIN400858)
抗原
See all TDP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-298, N-Term
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特异性
- The antibody recognizes human TDP1. Other species not tested.
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产品特性
- Synonyms: Tyrosyl-DNA phosphodiesterase 1
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纯化方法
- Protein-G affinity chromatography
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免疫原
- Recombinant human TDP1 (1-298 aa) purified from E. coli
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亚型
- IgG2b
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应用备注
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ELISA. Western blot: 1/1,000-1/2,000. Immunohistochemistry on Paraffin Sections: 5 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
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别名
- TDP1
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背景
- Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily and contains two PLD phosphodiesterase domains. Mutations in TDP1 are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1) by interfering with DNA transcription or by inducting apoptosis in postmitotic neurons.Synonyms: Tyrosyl-DNA phosphodiesterase 1
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基因ID
- 55775
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UniProt
- Q9NUW8
抗原
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