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CD59 抗体

This anti-CD59 antibody is a 小鼠 单克隆 antibody detecting CD59 in FACS 和 IHC (p). Suitable for 人, 猴, Baboon 和 Chimpanzee.
产品编号 ABIN400702
发货至: 中国

Quick Overview for CD59 抗体 (ABIN400702)

抗原

See all CD59 抗体
CD59

适用

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人, 猴, Baboon, Chimpanzee

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD59 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

P282 (H19)
  • 特异性

    Recognizes CD59 Glycoprotein.

    交叉反应 (详细)

    Species reactivity (expected):Baboon, Chimpanzee and Monkey.
    Species reactivity (tested):Human.

    产品特性

    Synonyms: MAC-inhibitory protein, Protectin, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MSK21,MACIF, MAC-IP, MIRL, HRF20, HRF-20, Membrane attack complex inhibition factor,Membrane inhibitor of reactive lysis, 20 kDa homologous restriction factor

    纯化方法

    Affinity Chromatography.

    免疫原

    Full length protein corresponding to Human CD59.

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: 2 μg/IE6 cells. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD59

    别名

    CD59

    背景

    CD59, an LY6 like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

    基因ID

    966

    UniProt

    P13987

    途径

    Complement System
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