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SIK2 抗体

This anti-SIK2 antibody is a 小鼠 单克隆 antibody detecting SIK2 in WB, IP, IF, ICC 和 IHC (p). Suitable for 人.
产品编号 ABIN400680
发货至: 中国

Quick Overview for SIK2 抗体 (ABIN400680)

抗原

See all SIK2 抗体
SIK2 (Salt-Inducible Kinase 2 (SIK2))

适用

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宿主

  • 30
  • 6
  • 2
小鼠

克隆类型

  • 33
  • 5
单克隆

标记

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This SIK2 antibody is un-conjugated

应用范围

  • 37
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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

S15G10
  • 产品特性

    Synonyms: SIK-2, SNF1LK2, QIK, Serine/threonine-protein kinase SIK2, Salt-inducible protein kinase 2,Serine/threonine-protein kinase SNF1-like kinase 2, Qin-induced kinase

    纯化方法

    Affinity Chromatography.

    免疫原

    Recombinant Human SIK2.

    亚型

    IgG1
  • 应用备注

    Western blot. Immunoprecipitation. Immunofluorescence. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.2 containing 0.09% Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    SIK2 (Salt-Inducible Kinase 2 (SIK2))

    别名

    SIK2

    背景

    Snf1lk2 belongs to the Ser/Thr protein kinase family, AMPK subfamily. It has one proteinkinase domain and one UBA domain. Snf1lk2 requires magnesium as a cofactor andphosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes. This potentiallymodulates the efficiency of insulin signal transduction. It also inhibits CREB activity byphosphorylating and repressing the CREB-specific coactivators, CRTC1-3. Snf1lk2 isactivated by phosphorylation on Thr-175 by STK11 in complex with STE20-relatedadapter-alpha (STRAD alpha) pseudo kinase and CAB39.

    UniProt

    Q9H0K1
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