TBK1 抗体 (AA 563-577)
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北京 101111
Quick Overview for TBK1 抗体 (AA 563-577) (ABIN400648)
抗原
See all TBK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 563-577
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特异性
- This antibody recognizes Human TANK-Binding Kinase 1 (TBK1/NAK).
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交叉反应 （详细）
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Species reactivity (expected):Bovine, Canine (Dog), Mouse and Rat.
Species reactivity (tested):Human. -
产品特性
- Synonyms: NAK, TANK-binding kinase 1, T2K, NF-kappa-B-activating kinase
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纯化方法
- Protein G Chromatography
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免疫原
- A synthetic peptide corresponding to amino acids 563-577 of Human TBK1 - KLHconjugated. AA Sequence: YYQFKKDKAERRLAYCRemarks: This sequence is 100% conserved between Human, Mouse, Rat, Dog and Cow.
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亚型
- IgG1
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anti-TANK-Binding Kinase 1 (TBK1) (AA 440-729) antibody
TBK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 150-181) antibodyTBK1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB16573 unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (pSer172) antibodyTBK1 适用: 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) (AA 9-310) antibodyTBK1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) antibodyKD Validated TBK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4650 unconjugated Recombinant Antibody
anti-TANK-Binding Kinase 1 (TBK1) antibodyKD Validated TBK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4645 unconjugated Recombinant Antibody
anti-TANK-Binding Kinase 1 (TBK1) (AA 364-585) antibodyTBK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TANK-Binding Kinase 1 (TBK1) antibodyKO Validated TBK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2145 unconjugated Recombinant Antibody
anti-TANK-Binding Kinase 1 (TBK1) antibodyKD Validated TBK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4640 unconjugated Recombinant Antibody
anti-TANK-Binding Kinase 1 (TBK1) (pSer172) antibodyKD Validated TBK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2150 unconjugated Recombinant Antibody
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应用备注
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Western Blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, 0.05 % Sodium Azide, 0.2 % Gelatin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- TBK1 (TANK-Binding Kinase 1 (TBK1))
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别名
- TBK1
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背景
- NFkappaB-activating kinase (NAK) also known as TANK binding kinase-1 (TBK1) or tumor necrosis factor receptor-associated factor 2-associated kinase (T2K) is a serine/threonine protein that belongs to the IkB kinase (IKK) family. Similar to IKK alpha and beta, NAK induces IkB degradation and NF-kB activity. NAK is activated by phorbol ester tumour promoters and growth factors, whereas catalytically inactive NAK specifically inhibits activation of NF-kB by protein kinase C-epsilon (PKCepsilon). NAK specifically phosphorylates IkB alpha on Serine 36 and NFkB subunit RelA (p65) on Serine 536. NAK is also known to interact with TANK, TRAF-2 and TRIF.Synonyms: NAK, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1
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基因ID
- 29110
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UniProt
- Q9UHD2
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
抗原
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