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PFKP 抗体 (C-Term)

Name: PFKP 抗体 (C-Term)
SKU: ABIN392744
Availability: OutOfStock

This anti-PFKP antibody is a 兔多克隆 antibody detecting PFKP in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 3+ publications.

All lanes : Anti-PFKP Antibody at 1:8000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. (PFKP 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (PFKP 抗体 (C-Term))

IHC (p)

2 images

(3 references)

产品编号 ABIN392744

发货至: 中国

Datasheet as PDF

Quick Overview for PFKP 抗体 (C-Term) (ABIN392744)

抗原

See all PFKP 抗体

PFKP (phosphofructokinase, Platelet (PFKP))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PFKP antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB03900

Discover our top product PFKP Primary Antibody

抗原表位
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2

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1

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AA 754-784, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This PFKP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 754-784 amino acids from the C-terminal region of human PFKP.

亚型

Ig Fraction
anti-phosphofructokinase, Platelet (PFKP) (AA 553-753) antibody
PFKP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-phosphofructokinase, Platelet (PFKP) (AA 247-473) antibody
PFKP 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-phosphofructokinase, Platelet (PFKP) (AA 354-570) antibody
PFKP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-phosphofructokinase, Platelet (PFKP) antibody
PFKP 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2E10 unconjugated

anti-phosphofructokinase, Platelet (PFKP) antibody
PFKP 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1D6 unconjugated

anti-phosphofructokinase, Platelet (PFKP) (AA 1-784) antibody
PFKP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-phosphofructokinase, Platelet (PFKP) (AA 1-784) antibody
PFKP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-phosphofructokinase, Platelet (PFKP) (Internal Region) antibody
PFKP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-phosphofructokinase, Platelet (PFKP) (AA 692-783) antibody
PFKP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-phosphofructokinase, Platelet (PFKP) (Internal Region) antibody
PFKP 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:8000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Bao, Mukai, Hishiki, Kubo, Ohmura, Sugiura, Matsuura, Nagahata, Hayakawa, Yamamoto, Fukuda, Saya, Suematsu, Minamishima: "Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo." in: Molecular cancer research : MCR, Vol. 11, Issue 9, pp. 973-85, (2013) (PubMed).

Yalcin, Clem, Simmons, Lane, Nelson, Clem, Brock, Siow, Wattenberg, Telang, Chesney: "Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 24223-32, (2009) (PubMed).

Moeller, Dumitrescu, Refetoff: "Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 12, pp. 2955-63, (2005) (PubMed).
抗原

PFKP (phosphofructokinase, Platelet (PFKP))

别名

PFKP

背景

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

分子量

85596

基因ID

5214

NCBI登录号

NP_001229268, NP_002618

UniProt

Q01813

途径

Warburg Effect