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- 抗原 See all PIM1 抗体
- PIM1 (Pim-1 Oncogene (PIM1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PIM1 antibody is generated from rabbits immunized with PIM1 recombinant protein.
- 克隆位点
- RB15686
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PIM1 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 133, (2017) (PubMed).
: "PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 15, pp. 5735-9, (2012) (PubMed).
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PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 133, (2017) (PubMed).
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- 抗原
- PIM1 (Pim-1 Oncogene (PIM1))
- 别名
- PIM1 (PIM1 产品)
- 背景
- PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
- 分子量
- 35686
- 基因ID
- 5292
- NCBI登录号
- NP_001230115, NP_002639
- UniProt
- P11309
- 途径
- Glycosaminoglycan Metabolic Process
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