PIM1 抗体 (C-Term)
Quick Overview for PIM1 抗体 (C-Term) (ABIN392440)
抗原
See all PIM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 374-404, C-Term
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预测反应
- B
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This PIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-404 amino acids from the C-terminal region of human PIM1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Patterns and Significance of PIM Kinases in Urothelial Carcinoma." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).
: "Molecular markers predicting lymph node metastasis in early esophageal cancer." in: Histology and histopathology, pp. 11618, (2015) (PubMed).
: "Prognostic impact of protein overexpression of the proto-oncogene PIM-1 in gastric cancer." in: Anticancer research, Vol. 29, Issue 11, pp. 4451-5, (2009) (PubMed).
: "Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation." in: The American journal of pathology, Vol. 175, Issue 1, pp. 400-11, (2009) (PubMed).
: "Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma." in: Cancer biology & therapy, Vol. 7, Issue 9, pp. 1352-9, (2008) (PubMed).
: "Comprehensive identification of proteins in Hodgkin lymphoma-derived Reed-Sternberg cells by LC-MS/MS." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 87, Issue 11, pp. 1113-24, (2007) (PubMed).
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: "Patterns and Significance of PIM Kinases in Urothelial Carcinoma." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).
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- PIM1 (Pim-1 Oncogene (PIM1))
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别名
- PIM1
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背景
- PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
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分子量
- 35686
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基因ID
- 5292
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NCBI登录号
- NP_001230115, NP_002639
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UniProt
- P11309
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途径
- Glycosaminoglycan Metabolic Process
抗原
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