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PIM1 抗体 (C-Term)

Cited in 6+ publications. This 兔 多克隆 anti-PIM1 antibody (Clone RB1285-RB1286) specifically detects PIM1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN392440
发货至: 中国
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Quick Overview for PIM1 抗体 (C-Term) (ABIN392440)

抗原

See all PIM1 抗体
PIM1 (Pim-1 Oncogene (PIM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PIM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1285-RB1286
  • 抗原表位

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    AA 374-404, C-Term

    预测反应

    B

    纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This PIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-404 amino acids from the C-terminal region of human PIM1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Albertson, Schmidt, Bearss, Tripp, Bearss, Liu: "Patterns and Significance of PIM Kinases in Urothelial Carcinoma." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).

    Plum, Warnecke-Eberz, Dhaouadi, Alakus, Drebber, Metzger, Prenzel, Hölscher, Bollschweiler: "Molecular markers predicting lymph node metastasis in early esophageal cancer." in: Histology and histopathology, pp. 11618, (2015) (PubMed).

    Warnecke-Eberz, Bollschweiler, Drebber, Metzger, Baldus, Hölscher, Mönig: "Prognostic impact of protein overexpression of the proto-oncogene PIM-1 in gastric cancer." in: Anticancer research, Vol. 29, Issue 11, pp. 4451-5, (2009) (PubMed).

    Chen, Kobayashi, Darmanin, Qiao, Gully, Zhao, Kondo, Wang, Wang, Yeung, Lee: "Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation." in: The American journal of pathology, Vol. 175, Issue 1, pp. 400-11, (2009) (PubMed).

    Reiser-Erkan, Erkan, Pan, Bekasi, Giese, Streit, Michalski, Friess, Kleeff: "Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma." in: Cancer biology & therapy, Vol. 7, Issue 9, pp. 1352-9, (2008) (PubMed).

    Wallentine, Kim, Seiler, Vaughn, Crockett, Tripp, Elenitoba-Johnson, Lim: "Comprehensive identification of proteins in Hodgkin lymphoma-derived Reed-Sternberg cells by LC-MS/MS." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 87, Issue 11, pp. 1113-24, (2007) (PubMed).

  • 抗原

    PIM1 (Pim-1 Oncogene (PIM1))

    别名

    PIM1

    背景

    PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.

    分子量

    35686

    基因ID

    5292

    NCBI登录号

    NP_001230115, NP_002639

    UniProt

    P11309

    途径

    Glycosaminoglycan Metabolic Process
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