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GCK 抗体 (C-Term)

Name: GCK 抗体 (C-Term)
SKU: ABIN392391
Availability: OutOfStock

This anti-GCK antibody (ABIN392391) is a Rabbit Polyclonal antibody detecting GCK in WB, IHC (p). Suitable for Human.

Western blot analysis of hGCK- (ABIN392391 and ABIN2842019) in Jurkat cell line lysates (35 μg/lane). (GCK 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (GCK 抗体 (C-Term))

IHC (p)

Western blot analysis of GCK (arrow) using rabbit polyclonal hGCK- (ABIN392391 and ABIN2842019). (GCK 抗体 (C-Term))

3 images

产品编号 ABIN392391

发货至: 中国

Datasheet as PDF

Quick Overview for GCK 抗体 (C-Term) (ABIN392391)

抗原

See all GCK 抗体

GCK (Glucokinase (Hexokinase 4) (GCK))

适用

人

宿主

兔

克隆类型

多克隆

标记

This GCK antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB05339

Discover our top product GCK Primary Antibody

抗原表位
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AA 403-433, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This GCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 403-433 amino acids from the C-terminal region of human GCK.

亚型

Ig Fraction
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibody
GCK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Glucokinase (Hexokinase 4) (GCK) antibody
GCK 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated

anti-Glucokinase (Hexokinase 4) (GCK) (AA 101-200) antibody
GCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Glucokinase (Hexokinase 4) (GCK) (AA 3-226) antibody
GCK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-300) antibody
GCK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Glucokinase (Hexokinase 4) (GCK) antibody
GCK 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibody
GCK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibody
GCK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Glucokinase (Hexokinase 4) (GCK) (AA 194-410) antibody
GCK 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glucokinase (Hexokinase 4) (GCK) (N-Term) antibody
GCK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

GCK (Glucokinase (Hexokinase 4) (GCK))

别名

GCK

背景

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in the gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), also called maturity onset diabetes of the young, type 2 (MODY2), mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

分子量

52191

基因ID

2645

NCBI登录号

NP_000153, NP_277042, NP_277043

UniProt

P35557

途径

MAPK Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process