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TBK1 抗体 (AA 150-181)

This anti-TBK1 antibody is a 兔 多克隆 antibody detecting TBK1 in WB 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN392371
发货至: 中国

Quick Overview for TBK1 抗体 (AA 150-181) (ABIN392371)

抗原

See all TBK1 抗体
TBK1 (TANK-Binding Kinase 1 (TBK1))

适用

  • 74
  • 43
  • 25
  • 7
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  • 5
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  • 2
  • 2
  • 1
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  • 1
人, 小鼠

宿主

  • 81
  • 4
  • 1

克隆类型

  • 74
  • 12
多克隆

标记

  • 57
  • 7
  • 7
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TBK1 antibody is un-conjugated

应用范围

  • 63
  • 48
  • 38
  • 13
  • 12
  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB16573
  • 抗原表位

    • 10
    • 9
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    • 6
    • 5
    • 4
    • 3
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    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-181

    预测反应

    Zf, X

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TBK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-181 amino acids from human TBK.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:2000. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Jiang, Song, Li, Xue, Deng, Li, Liu, Wang: "Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells." in: Mediators of inflammation, Vol. 2017, pp. 9891673, (2018) (PubMed).

  • 抗原

    TBK1 (TANK-Binding Kinase 1 (TBK1))

    别名

    TBK1

    背景

    The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TKB is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.

    分子量

    83642

    基因ID

    29110

    NCBI登录号

    NP_037386

    UniProt

    Q9UHD2

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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