ACVR1 抗体 (AA 132-162)
(2 references)Quick Overview for ACVR1 抗体 (AA 132-162) (ABIN392240)
抗原
See all ACVR1 (ACRV1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 132-162
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预测反应
- B, M, Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This Activin Receptor Type IA (ACVR1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-162 amino acids from the Central region of human Activin Receptor Type IA (ACVR1).
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亚型
- Ig Fraction
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anti-Activin Receptor Type I (ACRV1) (AA 21-120) antibody
ACRV1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E2C11 unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 21-120) antibodyACRV1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2C1E8 unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 132-162) antibodyACRV1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 208-340) antibodyACRV1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 20-125) antibodyACRV1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 21-120) antibodyACRV1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D5 unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 137-166) antibodyACRV1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34167 unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 85-123) antibodyACRV1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB6514 unconjugated
anti-Activin Receptor Type I (ACRV1) (N-Term) antibodyACRV1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 山羊, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type I (ACRV1) (N-Term) antibodyACRV1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 山羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury." in: American journal of physiology. Renal physiology, Vol. 293, Issue 5, pp. F1641-8, (2007) (PubMed).
: "A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma." in: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 9, pp. 3584-91, (2006) (PubMed).
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: "BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury." in: American journal of physiology. Renal physiology, Vol. 293, Issue 5, pp. F1641-8, (2007) (PubMed).
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- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
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别名
- Activin Receptor Type IA (ACVR1)
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背景
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors.
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分子量
- 57153
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基因ID
- 90
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NCBI登录号
- NP_001096, NP_001104537
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UniProt
- Q04771
抗原
-
