ACVR1 抗体 (N-Term)
-
- 抗原 See all ACVR1 (ACRV1) 抗体
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ACVR1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- TCKTPPSPGQ AVECCQGDWC NRNITAQLPT KGKSFPGTQN FHLEVGLIIL
- 预测反应
- Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against ACVR1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACVR1
- Top Product
- Discover our top product ACRV1 Primary Antibody
-
anti-Activin Receptor Type I (ACRV1) (AA 21-120) antibody
ACRV1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2C1E8 unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 132-162) antibodyACRV1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03507-03508 unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 132-162) antibodyACRV1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 208-340) antibodyACRV1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 20-125) antibodyACRV1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 85-123) antibodyACRV1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB6514 unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 137-166) antibodyACRV1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34167 unconjugated
anti-Activin Receptor Type I (ACRV1) (N-Term) antibodyACRV1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 山羊, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type I (ACRV1) (AA 208-340) antibodyACRV1 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type I (ACRV1) antibodyACRV1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 509 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
- 别名
- ACVR1 (ACRV1 产品)
- 别名
- ACTRI antibody, ACVR1A antibody, ACVRLK2 antibody, ALK2 antibody, FOP antibody, SKR1 antibody, TSRI antibody, ActR-IA antibody, ActR-I antibody, ActRIA antibody, Acvr antibody, Acvrlk2 antibody, Alk-2 antibody, Alk8 antibody, D330013D15Rik antibody, Tsk7L antibody, actri antibody, acvr1 antibody, acvr1-a antibody, acvr1-b antibody, acvr1a antibody, acvrlk2 antibody, alk-2 antibody, alk2 antibody, alk8 antibody, fop antibody, sax antibody, skr1 antibody, tsri antibody, xALK-2 antibody, activin A receptor type 1 antibody, activin A receptor, type 1 antibody, activin A receptor type 1 S homeolog antibody, ACVR1 antibody, Acvr1 antibody, acvr1.S antibody
- 背景
-
Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 is activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors.
Alias Symbols: ACTRI, ACVRLK2, ALK2, FOP, SKR1, TSRI, ACVR1A
Protein Interaction Partner: UBC, USP15, BMPR1A, ACVR1, INHBA, ACVR2A, PEG10, SMAD6, SMAD7, BAMBI, SMURF1, IGSF1, TSC22D1, TGFBR1, DCAF6, FGD6, FCHO1, PLEK, TTC17, RHEBL1, WDR61, RASL12, RASD2, PLEKHJ1, CDK14, NEK8, DUSP13, NUAK2, FKBP4, RAB6B, RAB17, UBXN1, FBXO30, RHOJ, PLEKHB1, UB
Protein Size: 509 - 分子量
- 55 kDa
- 基因ID
- 90
- NCBI登录号
- NM_001105, NP_001096
- UniProt
- Q04771
-
