PTK7 抗体 (N-Term)
Quick Overview for PTK7 抗体 (N-Term) (ABIN392230)
抗原
See all PTK7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 21-52, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CCK4 (PTK7) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human CCK4 (PTK7).
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000-1:2000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis." in: International journal of clinical and experimental pathology, Vol. 7, Issue 11, pp. 7881-9, (2014) (PubMed).
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: "PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis." in: International journal of clinical and experimental pathology, Vol. 7, Issue 11, pp. 7881-9, (2014) (PubMed).
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- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
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别名
- CCK4 (PTK7)
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背景
- CCK4 may function as a cell adhesion molecule. Although it belongs to the insuline receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.
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分子量
- 118392
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基因ID
- 5754
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NCBI登录号
- NP_001257327, NP_002812, NP_690619, NP_690620, NP_690621
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UniProt
- Q13308
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途径
- RTK signaling, Tube Formation
抗原
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