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PTK7 抗体 (N-Term)

This anti-PTK7 antibody is a 兔 多克隆 antibody detecting PTK7 in WB, IHC (p) 和 FACS. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN392230
发货至: 中国

Quick Overview for PTK7 抗体 (N-Term) (ABIN392230)

抗原

See all PTK7 抗体
PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

适用

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宿主

  • 50
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  • 1
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克隆类型

  • 53
  • 11
多克隆

标记

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This PTK7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB01501
  • 抗原表位

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    AA 21-52, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CCK4 (PTK7) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human CCK4 (PTK7).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000-1:2000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Wang, Li, Yin, Wang, Wang, Wei, Guo, Ma, Shi, Zhou, Wang: "PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis." in: International journal of clinical and experimental pathology, Vol. 7, Issue 11, pp. 7881-9, (2014) (PubMed).

  • 抗原

    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

    别名

    CCK4 (PTK7)

    背景

    CCK4 may function as a cell adhesion molecule. Although it belongs to the insuline receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.

    分子量

    118392

    基因ID

    5754

    NCBI登录号

    NP_001257327, NP_002812, NP_690619, NP_690620, NP_690621

    UniProt

    Q13308

    途径

    RTK signaling, Tube Formation
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