Desmoglein 2 抗体 (N-Term)
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Quick Overview for Desmoglein 2 抗体 (N-Term) (ABIN392225)
抗原
See all Desmoglein 2 (DSG2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 145-216, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This DSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-216 amino acids from the N-terminal region of human DSG2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Desmoglein 2 (DSG2)
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别名
- DSG2
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背景
- Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This protein is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in the DSG2 gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
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分子量
- 122294
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基因ID
- 1829
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NCBI登录号
- NP_001934
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UniProt
- Q14126
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途径
- Cell-Cell Junction Organization
抗原
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