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PTK6 抗体 (N-Term)

This anti-PTK6 antibody is a 兔 多克隆 antibody detecting PTK6 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN392105
发货至: 中国

Quick Overview for PTK6 抗体 (N-Term) (ABIN392105)

抗原

See all PTK6 抗体
PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

适用

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宿主

  • 83
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克隆类型

  • 85
  • 9
多克隆

标记

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This PTK6 antibody is un-conjugated

应用范围

  • 69
  • 41
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB3073-3074
  • 抗原表位

    • 25
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    AA 11-41, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This BRK (PTK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of human BRK (PTK6).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Xu, Ye, Wu, He, Tan, Xiao, Wu, Yu, Mai, Li, Peng, Huang, Li, Zhang, Zhu, Qin: "Overexpression of PTK6 predicts poor prognosis in bladder cancer patients." in: Journal of Cancer, Vol. 8, Issue 17, pp. 3464-3473, (2018) (PubMed).

    Chen, Ma, Cao, Huang, Zeng, Wen: "Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 317, (2014) (PubMed).

  • 抗原

    PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

    别名

    BRK (PTK6)

    背景

    PTK6 is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation.

    分子量

    51834

    基因ID

    5753

    NCBI登录号

    NP_001243287, NP_005966

    UniProt

    Q13882
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