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PTK6 抗体

PTK6 适用: 人 ELISA Monoclonal unconjugated
产品编号 ABIN966923
发货至: 中国
  • 抗原 See all PTK6 抗体
    PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))
    适用
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    克隆类型
    • 89
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    单克隆
    标记
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    This PTK6 antibody is un-conjugated
    应用范围
    • 77
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    ELISA
    特异性
    Ni-NTA purified truncated recombinant PTK6 expressed in E. Coli strain BL21 (DE3).
    纯化方法
    Antibodies are purified by protein A affinity chromatography
    亚型
    IgG2b
    Top Product
    Discover our top product PTK6 Primary Antibody
  • 应用备注
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    -20 °C
  • Park, Lee, Lee: "Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG." in: Journal of biochemistry, Vol. 119, Issue 2, pp. 235-9, (1997) (PubMed).

  • 抗原
    PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))
    别名
    PTK6 (PTK6 产品)
    别名
    BRK antibody, Sik antibody, Tksk antibody, tks antibody, zgc:153964 antibody, protein tyrosine kinase 6 antibody, PTK6 protein tyrosine kinase 6 antibody, PTK6 protein tyrosine kinase 6b antibody, PTK6 antibody, Ptk6 antibody, ptk6b antibody
    背景
    PTK6 (protein tyrosine kinase 6, BRK or FLJ42088),with 451-amino acid protein (about 51kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.
    基因ID
    5753
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