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BLK 抗体 (N-Term)

This anti-BLK antibody is a 兔 多克隆 antibody detecting BLK in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN392087
发货至: 中国

Quick Overview for BLK 抗体 (N-Term) (ABIN392087)

抗原

See all BLK 抗体
BLK (B Lymphoid Tyrosine Kinase (BLK))

适用

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  • 1
  • 1
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  • 1
人, 小鼠

宿主

  • 52
  • 11
  • 1

克隆类型

  • 54
  • 12
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
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This BLK antibody is un-conjugated

应用范围

  • 50
  • 35
  • 29
  • 13
  • 13
  • 6
  • 6
  • 4
  • 3
  • 3
  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB03107
  • 抗原表位

    • 15
    • 8
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This BLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BLK.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    BLK (B Lymphoid Tyrosine Kinase (BLK))

    别名

    BLK

    背景

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

    分子量

    57706

    基因ID

    640

    NCBI登录号

    NP_001706

    UniProt

    P51451

    途径

    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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