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PDGFRA 抗体 (AA 698-727)

Cited in 1 publication. This anti-PDGFRA antibody is a 兔 多克隆 antibody detecting PDGFRA in WB 和 IHC (p). Suitable for 小鼠.
产品编号 ABIN392024
发货至: 中国
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Quick Overview for PDGFRA 抗体 (AA 698-727) (ABIN392024)

抗原

See all PDGFRA 抗体
PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This PDGFRA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB11101
  • 抗原表位

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    AA 698-727

    预测反应

    C, Rat, X

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-727 amino acids from human PDGFRA.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:2000. IHC-P: 1:25. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Guan, Wei, Wu, Fang, Liao, Xiao, Li, Li: "Down-regulation of miR-218-2 and its host gene SLIT3 cooperate to promote invasion and progression of thyroid cancer." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 8, pp. E1334-44, (2013) (PubMed).

  • 抗原

    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

    别名

    PDGFRA

    背景

    PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

    分子量

    122670

    基因ID

    5156

    NCBI登录号

    NP_006197

    UniProt

    P16234

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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