PDGFRA 抗体 (AA 698-727)
Quick Overview for PDGFRA 抗体 (AA 698-727) (ABIN392024)
抗原
See all PDGFRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 698-727
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预测反应
- C, Rat, X
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-727 amino acids from human PDGFRA.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:2000. IHC-P: 1:25. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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Down-regulation of miR-218-2 and its host gene SLIT3 cooperate to promote invasion and progression of thyroid cancer." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 8, pp. E1334-44, (2013) (PubMed).
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Down-regulation of miR-218-2 and its host gene SLIT3 cooperate to promote invasion and progression of thyroid cancer." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 8, pp. E1334-44, (2013) (PubMed).
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- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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别名
- PDGFRA
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背景
- PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
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分子量
- 122670
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基因ID
- 5156
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NCBI登录号
- NP_006197
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UniProt
- P16234
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
抗原
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