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EPH Receptor B4 抗体

This anti-EPH Receptor B4 antibody is a 兔 多克隆 antibody detecting EPH Receptor B4 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN391924
发货至: 中国

Quick Overview for EPH Receptor B4 抗体 (ABIN391924)

抗原

See all EPH Receptor B4 (EPHB4) 抗体
EPH Receptor B4 (EPHB4)

适用

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宿主

  • 38
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克隆类型

  • 38
  • 21
多克隆

标记

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This EPH Receptor B4 antibody is un-conjugated

应用范围

  • 41
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB14731
  • 纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This EphB4 antibody is generated from rabbits immunized with human recombinant EphB4 protein.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Aslam, Abraham, Mansoor, Druker, Tyner, Keller: "PDGFR? reverses EphB4 signaling in alveolar rhabdomyosarcoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 17, pp. 6383-8, (2014) (PubMed).

    Brantley-Sieders, Jiang, Sarma, Badu-Nkansah, Walter, Shyr, Chen: "Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome." in: PLoS ONE, Vol. 6, Issue 9, pp. e24426, (2011) (PubMed).

  • 抗原

    EPH Receptor B4 (EPHB4)

    别名

    EphB4

    背景

    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.

    分子量

    108270

    基因ID

    2050

    NCBI登录号

    NP_004435

    UniProt

    P54760

    途径

    RTK signaling
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