EPH Receptor B2 抗体
Quick Overview for EPH Receptor B2 抗体 (ABIN391921)
抗原
See all EPH Receptor B2 (EPHB2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This EphB2 antibody is generated from rabbits immunized with a recombinant human EphB2 protein.
-
亚型
- Ig Fraction
-
-
anti-EPH Receptor B2 (EPHB2) antibody
EPHB2 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 48CT12-6-4 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 551-650) antibodyEPHB2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IHC (fro), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 226-325) antibodyEPHB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 17-200) antibodyEPHB2 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 2D12C6 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 1021-1050), (C-Term) antibodyEPHB2 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB01652 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 261-465) antibodyEPHB2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (C-Term) antibodyEPHB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (pTyr331) antibodyEPHB2 适用: 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (pTyr317) antibodyEPHB2 适用: 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (pTyr298) antibodyEPHB2 适用: 小鸡 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
- EPH Receptor B2 (EPHB2)
-
别名
- EphB2
-
背景
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.
-
分子量
- 117493
-
基因ID
- 2048
-
NCBI登录号
- NP_004433, NP_059145
-
UniProt
- P29323
-
途径
- RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
抗原
-
