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EPH Receptor B2 抗体 (C-Term)

This anti-EPH Receptor B2 antibody is a 兔 多克隆 antibody detecting EPH Receptor B2 in WB, IHC (p) 和 IF. Suitable for 人.
产品编号 ABIN391920
发货至: 中国

Quick Overview for EPH Receptor B2 抗体 (C-Term) (ABIN391920)

抗原

See all EPH Receptor B2 (EPHB2) 抗体
EPH Receptor B2 (EPHB2)

适用

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宿主

  • 48
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  • 2

克隆类型

  • 50
  • 20
多克隆

标记

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This EPH Receptor B2 antibody is un-conjugated

应用范围

  • 48
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

克隆位点

RB01652
  • 抗原表位

    • 8
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    AA 1021-1050, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This EphB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1021-1050 amino acids from the C-terminal region of human EphB2.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    EPH Receptor B2 (EPHB2)

    别名

    EphB2

    背景

    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.

    分子量

    117493

    基因ID

    2048

    NCBI登录号

    NP_004433, NP_059145

    UniProt

    P29323

    途径

    RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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