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MAK 抗体 (C-Term)

This anti-MAK antibody is a 兔 多克隆 antibody detecting MAK in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN391782
发货至: 中国

Quick Overview for MAK 抗体 (C-Term) (ABIN391782)

抗原

See all MAK 抗体
MAK (Male Germ Cell-Associated Kinase (MAK))

适用

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宿主

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克隆类型

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多克隆

标记

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This MAK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB3342
  • 抗原表位

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    AA 578-608, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 578-608 amino acids from the C-terminal region of human MAK.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Li, Rao, Zheng-Le, Hurd, Lillo, Khanna: "Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice." in: Cytoskeleton (Hoboken, N.J.), (2015) (PubMed).

    Tucker, Scheetz, Mullins, DeLuca, Hoffmann, Johnston, Jacobson, Sheffield, Stone: "Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E569-76, (2011) (PubMed).

  • 抗原

    MAK (Male Germ Cell-Associated Kinase (MAK))

    别名

    MAK

    背景

    MAK is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.

    分子量

    70581

    基因ID

    4117

    NCBI登录号

    NP_001229314, NP_001229886, NP_005897

    UniProt

    P20794
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