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CLK2 抗体 (N-Term)

Cited in 2+ publications. This 兔 多克隆 anti-CLK2 antibody (Clone RB3205) specifically detects CLK2 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN391766
发货至: 中国
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Quick Overview for CLK2 抗体 (N-Term) (ABIN391766)

抗原

See all CLK2 抗体
CLK2 (CDC-Like Kinase 2 (CLK2))

适用

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宿主

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克隆类型

  • 65
多克隆

标记

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This CLK2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB3205
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    AA 1-30, N-Term

    预测反应

    M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CLK2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Yoshida, Kim, Carver, Su, Weremowicz, Mulvey, Yamamoto, Brennan, Mei, Long, Yao, Polyak: "CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer." in: Cancer research, Vol. 75, Issue 7, pp. 1516-26, (2015) (PubMed).

    Nam, Seo, Park, An, Kim, Yang, Kim, Jeong, Jin: "Phosphorylation of CLK2 at serine 34 and threonine 127 by AKT controls cell survival after ionizing radiation." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31157-63, (2010) (PubMed).

  • 抗原

    CLK2 (CDC-Like Kinase 2 (CLK2))

    别名

    CLK2

    背景

    This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. This protein kinase is involved in the regulation of several cellular processes and may serve as a link between cell cycle progression, apoptosis, and telomere length regulation.

    分子量

    60090

    基因ID

    1196

    NCBI登录号

    NP_003984

    UniProt

    P49760

    途径

    Regulation of Carbohydrate Metabolic Process
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