VRK1 抗体 (AA 366-396)
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Quick Overview for VRK1 抗体 (AA 366-396) (ABIN391605)
抗原
See all VRK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 366-396
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This VRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-396 amino acids from the Central region of human VRK1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- VRK1 (Vaccinia Related Kinase 1 (VRK1))
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别名
- VRK1
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背景
- This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
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分子量
- 45476
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基因ID
- 7443
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NCBI登录号
- NP_003375
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UniProt
- Q99986
抗原
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