Complement Factor B 抗体 (Center)
Quick Overview for Complement Factor B 抗体 (Center) (ABIN391536)
抗原
See all Complement Factor B (CFB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 395-422, Center
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特异性
- This BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401~431 amino acids from the Center region of human BF.
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 AA from the Central region of human BF.
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亚型
- Ig Fraction
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应用备注
- WB = 1:1000, IHC (p) = 1:50-100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Complement Factor B (CFB)
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别名
- Complement Factor B
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背景
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BF is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Synonyms: Complement factor B, C3/C5 convertase, Properdin factor B, Glycine-rich beta glycoprotein, GBG, PBF2, Complement factor B Ba fragment, Complement factor B Bb fragment, BFD, BF, CFB -
分子量
- 85533 DA
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基因ID
- 629
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UniProt
- P00751
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途径
- Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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