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CD163 抗体 (N-Term)

CD163 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB18866 unconjugated
产品编号 ABIN391501
发货至: 中国
  • 抗原 See all CD163 抗体
    CD163
    抗原表位
    • 16
    • 16
    • 15
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 245-274, N-Term
    适用
    • 125
    • 50
    • 30
    • 29
    • 20
    • 5
    • 4
    • 1
    宿主
    • 105
    • 44
    • 1
    克隆类型
    • 92
    • 57
    • 1
    多克隆
    标记
    • 52
    • 18
    • 12
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD163 antibody is un-conjugated
    应用范围
    • 108
    • 71
    • 51
    • 38
    • 27
    • 26
    • 24
    • 24
    • 20
    • 18
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This CD163 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the N-terminal region of human CD163.
    克隆位点
    RB18866
    亚型
    Ig Fraction
    Top Product
    Discover our top product CD163 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    CD163
    别名
    CD163 (CD163 产品)
    别名
    DMBT1 antibody, CD163 antibody, CD163v2 antibody, CD163v3 antibody, M130 antibody, MM130 antibody, deleted in malignant brain tumors 1 protein-like antibody, CD163 molecule antibody, CD163 antigen antibody, LOC426820 antibody, CD163 antibody, Cd163 antibody
    背景
    CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.
    分子量
    125451
    基因ID
    9332
    NCBI登录号
    NP_004235, NP_981961
    UniProt
    Q86VB7
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