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MME 抗体 (AA 274-302)

This anti-MME antibody is a 兔 多克隆 antibody detecting MME in WB 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN391500
发货至: 中国

Quick Overview for MME 抗体 (AA 274-302) (ABIN391500)

抗原

See all MME 抗体
MME (Membrane Metallo-Endopeptidase (MME))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This MME antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

RB18820
  • 抗原表位

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    AA 274-302

    预测反应

    Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This MME antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-302 amino acids from the Central region of human MME.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    MME

    物质类

    Chemical

    背景

    MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

    分子量

    85514

    基因ID

    4311

    NCBI登录号

    NP_000893, NP_009218, NP_009219, NP_009220

    UniProt

    P08473

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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