NAE1 抗体 (C-Term)
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Quick Overview for NAE1 抗体 (C-Term) (ABIN391418)
抗原
See all NAE1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 430-459, C-Term
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预测反应
- Pr, M, Rat
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This NAE1 (APPBP1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-459 amino acids from the C-terminal region of human NAE1 (APPBP1).
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
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别名
- NAE1 (APPBP1)
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背景
- APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for cell cycle progression through the S/M checkpoint.
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分子量
- 60246
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基因ID
- 8883
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NCBI登录号
- NP_001018169, NP_001018170, NP_003896
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UniProt
- Q13564
抗原
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