CDKL5 抗体 (C-Term)
Quick Overview for CDKL5 抗体 (C-Term) (ABIN391362)
抗原
See all CDKL5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 982-1012, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This CDKL5 (STK9) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 982-1012 amino acids from the C-terminal region of human CDKL5 (STK9).
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亚型
- Ig Fraction
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anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (AA 722-831) antibody
CDKL5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (Internal Region) antibodyCDKL5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (AA 982-1012), (C-Term) antibodyCDKL5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (AA 790-921) antibodyCDKL5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (C-Term) antibodyCDKL5 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))
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别名
- CDKL5 (STK9)
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背景
- Defects in STK9, a dual-specificity serine/threonine kinase, are a cause of atypical Rett syndrome. Rett syndrome is an X-linked dominant disease. It is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Patients appear to develop normally until 6 to 18 months of age, then gradually lose speech and purposeful hand movements and develop microcephaly, seizures, autism, ataxia, intermittent hyperventilation, and stereotypic hand movements. After initial regression, the condition stabilizes and patients usually survive into adulthood. Rett syndrome due to CDKL5-associated mutations is characterized by a severe early-onset phenotype and atypical features such as infantile spasms.
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分子量
- 107519
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基因ID
- 6792
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NCBI登录号
- NP_001032420, NP_003150
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UniProt
- O76039
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途径
- Regulation of Cell Size
抗原
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