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CDKL5 抗体 (C-Term)

CDKL5 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN359452
发货至: 中国
  • 抗原 See all CDKL5 抗体
    CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 44
    • 31
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 55
    • 1
    克隆类型
    • 55
    • 1
    多克隆
    标记
    • 17
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDKL5 antibody is un-conjugated
    应用范围
    • 46
    • 27
    • 13
    • 13
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects CDKL5 (STK9) at C-term.
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human STK9.
    亚型
    Ig Fraction
    Top Product
    Discover our top product CDKL5 Primary Antibody
  • 应用备注
    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))
    别名
    CDKL5 / STK9 (CDKL5 产品)
    别名
    issx antibody, stk9 antibody, EIEE2 antibody, ISSX antibody, STK9 antibody, BC038161 antibody, Stk9 antibody, cyclin dependent kinase like 5 antibody, cyclin-dependent kinase-like 5 antibody, CDKL5 antibody, cdkl5 antibody, Cdkl5 antibody
    背景
    Defects in STK9, a dual-specificity serine/threonine kinase, are a cause of atypical Rett syndrome. Rett syndrome is an X-linked dominant disease. It is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Patients appear to develop normally until 6 to 18 months of age, then gradually lose speech and purposeful hand movements and develop microcephaly, seizures, autism, ataxia, intermittent hyperventilation, and stereotypic hand movements. After initial regression, the condition stabilizes and patients usually survive into adulthood. Rett syndrome due to CDKL5-associated mutations is characterized by a severe early-onset phenotype and atypical features such as infantile spasms.Synonyms: Cyclin-dependent kinase-like 5, Serine/threonine protein kinase 9
    分子量
    115537 Da
    基因ID
    6792, 9606
    UniProt
    O76039
    途径
    Regulation of Cell Size
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