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STRADB 抗体 (C-Term)

This anti-STRADB antibody is a 兔 多克隆 antibody detecting STRADB in WB. Suitable for 人.
产品编号 ABIN391172
发货至: 中国

Quick Overview for STRADB 抗体 (C-Term) (ABIN391172)

抗原

See all STRADB 抗体
STRADB (STE20-Related Kinase Adaptor beta (STRADB))

适用

  • 30
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宿主

  • 38
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克隆类型

  • 39
  • 1
多克隆

标记

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This STRADB antibody is un-conjugated

应用范围

  • 30
  • 20
  • 7
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  • 3
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Western Blotting (WB)

克隆位点

RB15723
  • 抗原表位

    • 9
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    • 1
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    AA 274-303, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This ALS2CR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-303 amino acids from the C-terminal region of human ALS2CR2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    STRADB (STE20-Related Kinase Adaptor beta (STRADB))

    别名

    ALS2CR2

    背景

    ALS2CR2 potentiates the antiapoptotic activity of XIAP by enhancing XIAP-mediated activation of JNK1 (MAPK8) and other JNK family members, but not by modulating XIAP-mediated caspase inhibition. Expression of a catalytically inactive TAK1 (MAP3K7) mutant blocks the XIAP/ALS2CR2 activation of JNK1. In vivo coprecipitation experiments show that both ALS2CR2 and XIAP interact with TAK1 and TRAF6. It has been proposed that XIAP-mediated protection from apoptosis utilizes both a JNK1 activation pathway that involves ALS2CR2 and a caspase inhibition pathway that is independent of ALS2CR2.

    分子量

    47026

    基因ID

    55437

    NCBI登录号

    NP_001193793, NP_061041

    UniProt

    Q9C0K7

    途径

    AMPK Signaling
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