ILK 抗体 (C-Term)
Quick Overview for ILK 抗体 (C-Term) (ABIN391105)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 391-421, C-Term
-
预测反应
- B, Rat
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This ILK2/ILK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-421 amino acids from the C-terminal region of human ILK2/ILK1.
-
亚型
- Ig Fraction
-
-
anti-Integrin-Linked Kinase (ILK) antibody
KO Validated ILK 适用: 人 WB, IHC, IHC (p), IP, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 97-244) antibodyILK 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 341-452) antibodyILK 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 301-400) antibodyILK 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 1-260) antibodyILK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 225-253) antibodyILK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 11-41) antibodyILK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (pThr173) antibodyILK 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 1-228) antibodyILK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (C-Term) antibodyILK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000. WB: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
- ILK (Integrin-Linked Kinase (ILK))
-
别名
- ILK2/ILK1
-
背景
- Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) is an ankyrin repeat containing 51 kDa receptor-proximate serine-threonine kinase (1), with a reported migration rate of 59K. This 451 amino acid protein interacts with the cytoplasmic domain of the beta-1 integrin subunit and contains sequence motifs found in pleckstrin homology domains capable of interacting with phosphoinositide lipids. ILK is an upstream regulator of Pi(3)K dependant activation of protein kinase B (PKB/AKT) and inhibition of glycogen synthase kinase 3 (GSK-3). ILK2 expression is associated with mediation of cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. ILK2 is overexpressed in some highly invasive tumor cell lines.
-
分子量
- 51419
-
基因ID
- 3611
-
NCBI登录号
- NP_001014794, NP_001014795, NP_001265370, NP_004508
-
UniProt
- Q13418
-
途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
抗原
-
