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PKM2 抗体 (C-Term)

This anti-PKM2 antibody is a 兔 多克隆 antibody detecting PKM2 in WB, IHC (p) 和 IF. Suitable for 人, 小鼠, 大鼠 和 猴. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN391053
发货至: 中国

Quick Overview for PKM2 抗体 (C-Term) (ABIN391053)

抗原

See all PKM2 抗体
PKM2 (Pyruvate Kinase M2 (PKM2))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This PKM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

克隆位点

RB3697
  • 抗原表位

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    AA 476-505, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:200. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

    有效期

    6 months
  • Kienzl, Sarg, Golderer, Obrist, Werner, Werner-Felmayer, Lindner, Maglione, Schneeberger, Margreiter, Brandacher: "Proteomic profiling of acute cardiac allograft rejection." in: Transplantation, Vol. 88, Issue 4, pp. 553-60, (2009) (PubMed).

  • 抗原

    PKM2 (Pyruvate Kinase M2 (PKM2))

    别名

    PKM2

    背景

    There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

    分子量

    57937

    基因ID

    5315

    NCBI登录号

    NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271

    UniProt

    P14618

    途径

    Warburg Effect
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