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PDK3 抗体 (N-Term)

This anti-PDK3 antibody is a 兔 多克隆 antibody detecting PDK3 in WB. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN391038
发货至: 中国

Quick Overview for PDK3 抗体 (N-Term) (ABIN391038)

抗原

See all PDK3 抗体
PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

适用

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宿主

  • 47
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克隆类型

  • 47
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多克隆

标记

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This PDK3 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB3039
  • 抗原表位

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    AA 1-30, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PDK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDK3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Halim, Mcfate, Mohyeldin, Okagaki, Korotchkina, Patel, Jeoung, Harris, Schell, Verma: "Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons." in: Glia, Vol. 58, Issue 10, pp. 1168-76, (2010) (PubMed).

    McFate, Mohyeldin, Lu, Thakar, Henriques, Halim, Wu, Schell, Tsang, Teahan, Zhou, Califano, Jeoung, Harris, Verma: "Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 33, pp. 22700-8, (2008) (PubMed).

  • 抗原

    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

    别名

    PDK3

    背景

    PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

    分子量

    46939

    基因ID

    5165

    NCBI登录号

    NP_001135858, NP_005382

    UniProt

    Q15120

    途径

    PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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